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Which of the following statements is true regarding naloxone administration?

  1. It should be given every 5 minutes

  2. It should only be used on children

  3. It can be repeated every 2 to 3 minutes if symptoms persist

  4. It is not effective if given in high doses

The correct answer is: It can be repeated every 2 to 3 minutes if symptoms persist

The correct statement regarding naloxone administration is that it can be repeated every 2 to 3 minutes if symptoms persist. Naloxone is an opioid antagonist used to reverse the effects of opioid overdose, and its administration may need to be repeated due to the duration of action of the opioids in the system. If an individual is still showing signs of respiratory depression or decreased consciousness after the initial dose, administering additional doses of naloxone every 2 to 3 minutes is appropriate until the person responds or emergency medical services arrive. This is essential because naloxone's effects may wear off before the opioid has left the bloodstream, leading to a return of respiratory depression. Therefore, careful monitoring of the patient's response is crucial. Other options do not convey accurate information. While naloxone can be administered multiple times, the recommendation of every 5 minutes may not be as effective as the more immediate 2 to 3 minutes if symptoms persist. Naloxone is not limited to use in children; it is effective for individuals of all ages experiencing an opioid overdose. Lastly, high doses of naloxone are typically not recommended because it can lead to adverse effects, but the idea that it is ineffective in high doses can be misleading. Proper dosing